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Ravindranath V, Shivakumar BR, Anandatheerthavarada HK

These sustained-release formulations and delivery methods can be administered through either percutaneous endoscopic gastro-jejunostomy tubes or mini-pumps, and are designed to provide a more consistent and controlled release of L-DOPA over an extended period of time, thereby reducing the likelihood of non-physiological pulsatile striatal dopamine receptor stimulation and maladaptive neuronal responses [54]
