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These signs can include a loss of appetite, nausea, tiredness, stomach pain and a yellowing of the skin and eyes (jaundice)
While the most common cause of hypothyroidism worldwide is iodine deficiency, in the United States, its Hashimotos thyroiditis, an autoimmune condition where the immune system creates antibodies that attack thyroid gland tissue [3]

Scand J Immunol 40(6):601608 Nguyen T et al (2016) Novel identification and characterisation of Transient receptor potential melastatin 3 ion channels on Natural Killer cells and B lymphocytes: effects on cell signalling in Chronic fatigue syndrome/Myalgic encephalomyelitis patients
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