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Description
Key points Mechanisms by which microbes might cause rheumatoid arthritis (RA) or spondyloarthritis (SpA) include molecular mimicry, microbial translocation, dysregulation of mucosal immunity, production of immunomodulatory metabolites and immune cell trafficking

Rainey-Smith SR, Gu Y, Gardener SL, et al

What have we seen in people
These last two mechanisms are ways in which also non-redox-active metals (e.g., As, Cd, Co, Hg, Mn, Ni, Pb, Zn) can provoke oxidative stress
