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Furthermore, the inhibition of glycolytic enzymes would cause the cell to shift its reliance on glycolysis to the pentose phosphate shunt, thus uncoupling the production of ATP and pyruvate from glycolysis and contributing to the growing anaerobic environment found in AD brain (133)

doi: 10.1002/humu.23315 40

* Correspondence: Giovanni Biggio, [email protected];[email protected] Mencacci, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers