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The NQO2 gene was suggested to be an important factor in Parkinsons disease, and promoter polymorphisms were associated with disease susceptibility 31,32

The ATM specific kinase inhibitor KU60019 (Tocris, UK) was dissolved in DMSO to 100 mM then diluted to 5 M directly into media
Together, these results are consistent with adenosine uptake via ENT1, rather than activation of ADORA2b, followed by deamination of adenosine itself or its metabolite AMP into inosine and IMP by adenosine deaminase 29 or RBC-specific AMP deaminase 3

The Level of Concern assigned to an IS for availability is based on the needed availability of the information maintained, processed, and transmitted by the systems for mission accomplishment, and how much tolerance for delay is allowed
