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Description
New nsp8 isoform suggests mechanism for tuning viral RNA synthesis

Inactivation of GPX4-dependent antioxidant defense leads to the accumulation of the lipid peroxides, which is a trigger of ferroptosis

These results could stem from greater or earlier effects of oxidative stress on the sensorimotor compared to the frontal cortex

Proc Natl Acad Sci USA 109:67046709
