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[18] Patients and carers should be aware of important safety considerations with these medicines: Amitriptyline, gabapentin, and pregabalin can cause sedation and impair the ability to drive or operate machinery
As a positive control, treatment with 10 mM DEM did induce nuclear localization of DAF-16 (Figure 2figure supplement 2), consistent with this challenge inducing acute stress

DOI: 10.1113/jphysiol.2013.255364

Im literally doing these things in real time with people, and you actually get to see what happens
