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Doses above 100mg daily show diminishing returns in NNMT inhibition the enzyme inhibition curve plateaus beyond 150mg while increasing the risk of methylation pathway disruption and homocysteine elevation
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[DOI] [PubMed] [Google Scholar] Feil V.J., Bakke J.E., Larsen G.L., Gustafsson B.E
The inhibition mechanisms of PAO were both GSH-dependent and independent
