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Moreover, although the autophagy of mitochondria (mitophagy) may sequester iron in mitophagosomes to prevent iron from releasing into the cytoplasm in the early stages of iron overload, extensive mitophagy can conversely trigger Fe 2+ liberation, elevate cytosolic Fe 2+ levels, and amplify ferroptosis (Yu et al., 2022
Cardozo et al
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[DOI] [PMC free article] [PubMed] [Google Scholar] 52.Tolra R., Martos S., Hajiboland R., Poschenrieder C
