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It includes some heartburn medicines including proton pump inhibitors (PPIs) such as esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole, H2 blockers such as famotidine and certain diabetes medicines such as metformin

Indeed, such abnormal presence of mitochondria in circulating red blood cells causes increased oxygen consumption, ROS generation, and hemolysis in SCD patients 50,51
[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Sikdar S., Papadopoulou M., Dubois J

Modulation of the immune system by UV radiation: more than just the effects of vitamin D
