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Common causes include hormonal changes, polycystic ovary syndrome (PCOS), the use of birth control pills, and thyroid dysfunction

Research Overview Understanding BPC-157 BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide whose 15-amino-acid sequence was derived from a larger gastric protective protein first characterised by Predrag Sikiric and colleagues at the University of Zagreb in the early 1990s

Each component has attracted attention in experimental models related to cellular signaling, tissue remodeling, and regenerative biology

Tissue Eng B Rev 17:165176 Lovric-Bencic M, Sikiric P, Hanzevacki JS, Seiwerth S, Rogic D, Kusec V, Aralica G, Konjevoda P, Batelja L, Blagaic AB (2004) Doxorubicine-congestive heart failure-increased big endothelin-1 plasma concentration: reversal by amlodipine, losartan, and gastric pentadecapeptide BPC157 in rat and mouse