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For example, both D1- and D2-like receptors have been shown to activate all three members of the MAPK family: p38 MAPK, JNK, and ERK1/2

[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Culleton BF, Larson MG, Kannel WB, Levy D

Sun X, Klingbeil O, Lu B, Wu C, Ballon C, Ouyang M, et al

These molecules prevent cumulative cellular damage associated with chronic oxidative stress, which contributes to inflammatory, neurodegenerative processes, premature aging and a range of chronic diseases [31], non-communicable diseases such as cardiovascular, neurodegenerative, certain types of cancer and conditions related to premature ageing [14, 32]