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While such models provide significant mechanistic insights into APAP-induced hepatotoxicity, including pathways related to oxidative stress, mitochondrial dysfunction, and inflammasome activation, they may not fully recapitulate the complexity of human physiology
Ischemia/reperfusion injury, angiogenesis, and EPC function 4
Excess iron is retained in ferritin during iron overload, where it binds nuclear receptor coactivator 4 (NOCA4)
Joiner WJ (2016) Unraveling the evolutionary determinants of sleep
