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The BBB in neurodegenerative diseases The BBB in Alzheimer's disease Primary pathological features of Alzheimer's disease include extracellular senile plaques composed of amyloid beta (A) fibers and intracellular neurofibrillary tangles formed by tau proteins[40]

A recent study identified FSP1 as a transcriptional target of Nrf2

In addition, L-theanine directly reduced the mRNA expression of Toll-like receptors (TLRs) (TLR-2, TLR-4) and inflammatory cytokines (TNF-, IFN-, and IL-2), enhanced the proliferation of T lymphocytes and regulated the intestinal mucosal immune response and inflammation

[DOI] [PubMed] [Google Scholar] 73.Mahagita C, Grassl SM, Piyachaturawat P, Ballatori N