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In summary, although evidence for single intervention strategies varies, given the complexity of CP/CPPS pathology, the most feasible future direction lies in constructing multi-target combination intervention regimens covering anti-inflammation + antioxidation + endocrine correction + microecological regulation based on patient phenotypic stratification, with the aim of achieving the dual goals of symptom relief and fertility protection ( Table 1 )

10.1016/j.jep.2009.03.030 J

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DNMTs fulfill complementary roles in order to maintain the methylation patterns in mammals