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[PubMed] [Google Scholar] Gimenez-Llort L, Ahlbom E, Dare E, Vahter M, Ogren S, Ceccatelli S

NADPH oxidase, activated by hyperglycemia, generates ROS in vascular and immune cells, contributing to endothelial dysfunction and inflammatory signaling [21]

In other words, my research and personal experience has taught me that both enhancing chemo/radiation while reducing collateral damage aka side effects of toxic therapies should be a cancer patients primary focus

If one considers that the Nrf2 transcription factor is transactivated following oxidative stress so as to stimulate autophagic flux (106,107), it is possible that taurine can attenuate the expression levels of Nrf2 transcription factor in the cerebrum of As2O3-exposed mice (103)