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Grade 3 sprain (severe)

Preparation of cigarette smoke extract CSE was prepared according to the previous study ( In vitro experiment Human alveolar epithelial A549 cells were purchased from the China Infrastructure of Cell Line Resource

Potential side effects include headaches, sweating, hypertension, insomnia, and agitation

the FDA has stated it lacks sufficient information to know whether the substance would cause harm when administered to humans Evidence snapshot: The evidence base is almost entirely preclinical, decades of animal (largely rat) studies, mostly from one Croatian research group (Sikiric et al., University of Zagreb), with a single small human trial under the brand name "Bepecin" (around 2015) that did not lead to any FDA-approved use