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By being implicated in the pathophysiology of atherosclerosis and incorporated into ASCVD risk assessment models, lipoproteins are important prognostic indicators of cardiovascular health

10.1038/s41580-020-0230-3 10.1038/s41580-020-0230-3 [DOI] [PubMed] [Google Scholar] Sies H, Belousov VV, Chandel NS et al (2022) Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

High concentrations of ROS can oxidize mitochondrial proteins, lipids, and nucleic acids, cause cell dysfunction, damage the ability of cells to maintain energy levels, cause energy exhaustion, damage and death of neurons, and change the excitability of neurons, thus reducing the threshold of seizures (6, 7)

Classen S, Zander T, Eggle D, Chemnitz JM, Brors B, Bchmann I, Popov A, Beyer M, Eils R, Debey S, Schultze JL: Human resting CD4+ T cells are constitutively inhibited by TGF beta under steady-state conditions