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Together, they provide systemic protective effects across multiple organs, maintaining vascular integrity and reducing reperfusion-related oxidative damage in experimental ischemia models

Canada Researchers have also found that it might play a role in other regulatory processes, such as boosting mitochondrial function and modulating the secretion of hormones like growth hormone and cortisol, which are critical for overall bodily function

(3) Y Asadi, R K Moundounga, A Chakroborty, A Pokokiri, and H Wang (2025) FOXOs and their roles in acute and chronic neurological disorders Frontiers in Molecular Bioscience

Contrary to these results, a subsequent randomized double-blind placebo-controlled clinical trial, wherein IN-OXT was administered daily within 12 days of trauma for 8 days and assessments, conducted at baseline and 1.5 months post-trauma, found that IN-OXT reduced PTSD, depression, and anxiety, even at follow-ups 6 months post-trauma [177,178]
