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4 Current challenges and prospects 4.1 Therapeutic targeting potential of TGF- 4.1.1 TGF- downstream effectors The therapeutic targeting of TGF- and its downstream effectors, particularly the Smad proteins, presents a promising avenue in fibrosis treatment

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March 22 Product: Italfarmaco/ITFs Duvyzat Indication : Duchenne muscular dystrophy Duchenne muscular dystrophy (DMD) patients have their third new treatment option in nine months after the FDA approved Italfarmacos Duvyzat, a nonsteroidal oral drug to be sold by newly incorporated U.S

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