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10.1016/j.ccr.2007.08.004 Cancer Cell 54 GillbergL.OrskovA

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As the feasibility of large-scale production, for example, the size and shape, ratios of the weight and volume to the reaction volume, and stirring conditions employed in this study would be reproducible when increasing the reaction volume to 1,000 mL for repeated batch reactions of NsPCS immobilized on both the cellulose sponge and MCC

Additionally, several studies have documented paradoxical activation of MAPK pathway during preclinical testing or clinical trials of BRAF inhibitors in pLGGs (63, 64)