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Dihexa and Nlel -AnglV both promoted spinogenesis and enhance synaptogenesis in cultured rat hippocampal neurons
C.SawaA.JaffreyS.BlackshawS.BarrowR

Two decades of peer-reviewed dermatology literature back both halves: controlled micro-injury triggers measurable collagen induction, and the resulting micro-channels enhance topical delivery of actives that otherwise can't cross the skin barrier at meaningful concentrations

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