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A coffee enema involves inserting a solution of organic and mold-free, brewed coffee into the colon via the rectum

Reconstituting too many vials at once Problem : Excess peptides expire before use (28-day window)

Advances in high-resolution technologies such as single-cell omics, spatial metabolomics, and imaging mass spectrometry have progressively unveiled the metabolic heterogeneity landscape within CRC [130, 131]

Reproducibility analysis of MIND changes and gene expression To determine the reliability of between-group MIND discrepancies in the two groups, we tested whether the MIND disparities were influenced by variations of eTIV, image quality (Euler index), and scanner