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Both metformin and the PPI (omeprazole) can contribute to B12 deficiency

Spondylocheirodysplastic EhlersDanlos syndrome (SCD-EDS) and the mutant zinc transporter ZIP13

J Pharmacol Exp Ther 313:870876

[DOI] [PMC free article] [PubMed] [Google Scholar] 302.Esposito M., Campanati A., Giunta A., Calianno G., Bianchi L., Diotallevi F., Offidani A.M., Fargnoli M.C