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consequently, its discussion has been trimmed and moved to Future Directions, explicitly acknowledging the absence of clinical evidence and the PK uncertainties (dose, timing, BBB penetration, and formulation effects) relevant to rapid ascent scenarios
Conclusions The current paradigm is that somatic SCs turn over slowly to protect their DNA from damage, while CPs divide actively to regenerate tissue

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Meier Burgisser G, Evrova O, Calcagni M, Scalera C, Giovanoli P, Buschmann J
