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Studies suggest that unexplained elevated B12 may be associated with an underlying malignancy, though this risk varies considerably depending on the population studied, degree of elevation, and persistence of high levels

Br Med J 1(3248):553 Harvey CB, Bassett JD, Maruvada P, Yen PM, Williams GR (2007) The rat thyroid hormone receptor (TR) 3 displays cell-, TR isoform-, and thyroid hormone response element-specific actions

This, almost single-handedly hinders the Nrf2 inhibitors to be translated from laboratories to clinics

Gehlhaar, et al
