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3 Advances in emerging drug therapies: genetically targeted therapies TDP-43 is an RNA-binding protein, and cytoplasmic TDP-43 aggregates are present in sporadic and familial ALS, in addition to familial ALS caused by mutations in SOD1 , and its aberrant aggregation and aberrant function have been implicated in the pathogenesis of ALS (31, 32)
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BPC-157 also counteracted NSAID-mediated lesions and arthritis [2, 31, 32]
Melatonin protects retinal pigment epithelium cells against ferroptosis in amd via the pi3k/akt/mdm2/p53 pathway
