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Due to their high vitamin K content, excessive consumption of Brussels sprouts may interfere with anticoagulant medications (e.g., warfarin), reducing their effectiveness and potentially increasing the risk of blood clots

While corticosteroid injections can reduce pain in some cases, repeated use may not always be ideal for tendon health

The headline results, as released in the Eli Lilly investor communication and aligned with the study design paper by Giblin and colleagues published in Diabetes, Obesity and Metabolism in 2026, are unusually strong for a Phase 3 obesity trial: Retatrutide 12 mg: mean body-weight reduction of 28.7 percent, roughly 32.3 kg (about 71.2 lbs) from baseline

PAO is described as one of the most potent GSTP1 inhibitors, with a K i value of 90 nM, which binds both the enzyme active site and C101 at the dimer interface