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Description
Melatonin is synthesized mainly in the pinealocytes of the pineal gland through the methylation of N-acetylserotonin, which is formed by the acetylation of 5-HT, a derivative of tryptophan, by aralkylamine N-acetyltransferase, followed by methylation via acetylserotonin-O-methyltransferase (ASMT)
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