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The major metabolites of administered panduratin A were identified in feces as oxidation and dioxidation products

The bioenergetic status and microenvironment of the three metabolic states indicate that differences in metabolic activity are unlikely to have been influenced by differences in tissue perfusion, the presence of necrosis, differences in cell proliferation or the presence of immune cell infiltrates, but rather represent tumour-cell-intrinsic metabolic phenotypes

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Researchers working in warmer environments should be especially attentive to minimizing the time a reconstituted vial spends unrefrigerated