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And get this: researchers have known for decades that homocysteine inches up as women go through the menopause transition

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Following the catabolism of glucose in the cytoplasm as part of glycolysis, the generated pyruvate is transported to the mitochondrial matrix, where it feeds into the TCA, undergoing oxidation to reduce NAD + to NADH, which is the main electron donor of the ETC 87

Its particularly focused on visceral and abdominal adipose tissue, which is exactly the stubborn midsection fat patients complain about most