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Activation of the TMAO-induced endothelial NLRP3 inflammasome was reduced by a mitochondrial ROS scavenger or SIRT3 overexpression in human umbilical vein endothelial cells (HUVECs), which suggested that the activation was mediated in part by inhibition of the SIRT3-SOD2-mtROS signaling pathway (Zhou et al., 2010
However, food doesn't provide as much ALA as you usually get through supplements
Quick-freeze, deep-etch visualization of the axonal cytoskeleton Trends Neurosci 1986
J Lipid Res 56: 14811491, 2015
