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By inhibiting cyclooxygenase (COX) enzymes, NSAIDs cause a decrease in the synthesis of prostaglandins that stimulate production of protective mucus and acid-buffering bicarbonate in the digestive tract
Correspondingly, inhibition of caspase-3 activation by Q-VD substantially reduced NET formation in WT neutrophils under all four stimuli, lowering NET levels to those observed in XKR8 KO cells (Extended Data Fig
This methodology shares similarities with PDT, where light is used instead of ultrasound to activate sensitizers
[PubMed] [Google Scholar] Wells C., Brennan S., Keon M., Ooi L
