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A 2025 systematic review in the American Journal of Sports Medicine confirmed preclinical support across tendon, ligament, muscle, and bone repair models while explicitly noting the absence of human clinical trial data (DOI: 10.1177/15563316251355551)
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The 21-day room temperature limit for brand-name pens reflects this accelerated timeline
[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Fasano A
