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A previous review on OOT for knee OA reinforced this finding, suggesting that while short to medium-term results were encouraging, the included RCTs exhibited discernible methodological constraints [8]
10.1016/j.omtn.2022.03.020 7 ChenH.WangL.LiuJ.WanZ.ZhouL.LiaoH.et al (2023)

Superoxide radical anion, generated from the enzyme xanthine oxidase (XO) plays an important role in the pathogenesis of ischemia-induced tissue injury (Vickenson and George 2020)

The bad news, however, is that enzymes prioritize ethanol, and only after theyre done metabolizing them can they focus on methanol
