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En casos de lesin aguda algunos protocolos reparten la dosis en: 2 veces al da (maana + noche) para mantener niveles estables
[DOI] [PMC free article] [PubMed] [Google Scholar] 129.Chen X.L., Dodd G., Kunsch C

Allosteric SHP2 inhibitor, IACS-13909, overcomes EGFR-dependent and EGFR-independent resistance mechanisms toward osimertinib

& Ogino, K
