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Physiologically, the breakdown of dipeptides into free amino acids is facilitated by dipeptidyl-peptidase-4 99 , a cell surface enzyme found in several cell types, including endothelial cells and the brush border in the intestinal mucosa, and is present in several strains of intestinal microbiota, existing in a soluble form in the bloodstream 100,101

Also, in subtotal or total pancreatic necrosis, it is prudent to use a proton pump inhibitor on a daily basis because of the likelihood that bicarbonate secretion by the pancreas is severely diminished rendering the patient susceptible to a duodenal ulcer

10.1002/jmv.1890150110 40

[DOI] [PMC free article] [PubMed] [Google Scholar] 104.Boachie J., Adaikalakoteswari A., Samavat J., Saravanan P