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Evidence from type 1 diabetes also points to an increase in GSH utilization, which in itself was associated with poorer glucose control.The perfect storm of obesity, oxidative stress, inflammation, adipocyte dysfunction, and the related metabolic abnormalities may also be linked by glutathione depletion

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They are considered potential alternatives to traditional antibiotics due to their antimicrobial and antioxidant properties ( Over the past decade, rapid advances in genomics, metabolomics, and systems biology have transformed our understanding of both anthraquinone and flavonoid metabolism in plants

Biochem Cell Biol 99(3):385395 Long M, Smouha EE, Qiu D, Li F, Johnson F, Luft B (2004) Flavanoid of Drynaria fortunei protects against gentamicin ototoxicity