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The crystal structures of the receptor protein were collected from the RCSB Protein Data Bank (PDB)
For TBI, the step-down protocol from 30 ml to 10 ml per day after the initial 14-day intensive period reflects the transition from acute neuroprotection to sustained recovery support

As a result, bacterial LPSs become available to immune cells of the host, recognized by PPRs on their surface, and activate a pro-inflammatory immune response

doi: 10.1111/j.1365-2265.2008.03487.x 212 DasLGuptaNDuttaPWaliaRVaipheiKRaiAet al
