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Patients with early Lebers disease (hereditary optic nerve atrophy) who were treated with cyanocobalamin suffered severe and swift optic atrophy

Additionally, ASXL1 was reported to associate with components of the H3K27me3-specific PRC2 complex, nuclear hormone receptors, BRD4 and MLL3/4 and therefore functions as a context-specific gene regulator 7,10

These results indicate that the dimer formation of GSTOs and CLICs is very important for their biological function

Martino, T
