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Conversely, Compound 32 , with a synthetic accessibility score of 3.23 and MW of 340.80 g/mol, higher than that of Compound 31 , was synthesized via a multi-step reaction ( 35 , yielding chloroindane methyl ester 36 , which, after chiral resolution using HPLC, afforded Compound 32 (Scheme 5) (Humphrey, 2014)

The enzyme superoxide dismutase converts superoxide to hydrogen peroxide, which can then be utilized to form the oxidant hypochlorous acid via the azurophilic granule enzyme myeloperoxidase [149]

While many vitamins and minerals are required in pregnancy, they should be taken in carefully controlled amounts

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