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Transgenicmouse models for lung cancer
Besides inhibiting the Xc- antiporter, erastin is also an activator of the mitochondrial voltage-dependent-anion channel (VDAC) by reversing the inhibitory effect of tubulin on VDAC, thus increasing oxidative phosphorylation, ATP, ROS production and mitochondrial membrane permeabilization
Med 3 , 371387.e9 (2022)
Improving the dysregulation of FoxO1 activity is a potential therapy for alleviating diabetic kidney disease
