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In conclusion, ROS lie at the heart of PCOS pathogenesis, where elevated ROS levels damage oocytes and GCsimpairing follicular development and maturation and contributing to poor oocyte quality, disrupted ovulation and infertilitywhile also undermining insulin signaling and driving androgen overproduction to integrate metabolic and endocrine dysfunctions

Another miRNA shown to target mTOR is miR-193a-5p involved in regulation of migration and invasion in vitro and metastasis in vivo in NSCLC (Yu et al., 2014)

Symptomatic versus asymptomatic intervertebral disc degeneration: is inflammation the key

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