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This indicates a multiregional enhanced oxidative stress leading to an impairment to the redox balance
[DOI] [PubMed] [Google Scholar] 69.Wang Y., Yen F.S., Zhu X.G., Timson R.C., Weber R., Xing C., Liu Y., Allwein B., Luo H., Yeh H.W., et al

Elafin, an endogenous Ser protease inhibitor, was found to be significantly reduced in the small intestinal epithelium of patients with active CD

No convincing relation between a known biological effect of these drugs and clinical response to them in RA has yet been demonstrated
