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Mutagenic definition of a papain-like catalytic triad, sufficiency of the N-terminal domain for single-site core catalytic enzyme acylation, and C-terminal domain for augmentative metal activation of a eukaryotic phytochelatin synthase

2.13.1.6 SAMP8 mice SAMP8 (Senescence-Accelerated Mouse Prone 8) mice, a spontaneous AD model, exhibit age-related cognitive decline, oxidative damage, and impaired BBB function
