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ANGPTL3 inhibition may, however, have the advantage of greater lowering of plasma LDL cholesterol and could specifically address elevated LDL cholesterol in familial hypercholesterolaemia refractory to standard drug therapies

[DOI] [PMC free article] [PubMed] [Google Scholar] 646.Komiya I., Tomoyose T., Yagi N., Ouchi G., Wakugami T

These findings indicate that SLIRP-mediated stabilization of mitochondrial transcripts plays a critical regulatory role in maintaining mitochondrial architecture and respiratory function in skeletal muscle

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