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The CDC says there is no difference in effectiveness or side effects if people get those vaccines simultaneously, although one in each arm might be more comfortable

18 A study in 2003 compared oral versus sublingual cyano-B12 (500 g per day for 8 weeks), and found that both increased B12 levels significantly without a significant difference between the two

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The BOND project has set cutoffs for serum B12 based on the relationship between serum B12 and serum methylmalonic acid, the latter a relatively specific and sensitive functional biomarker of B12 status (Section 22b.2.4)
