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Current evidence supports glutathione's potential as a depigmenting agent but underscores the need for rigorous, large-scale clinical trials to establish long-term safety, optimal dosing, and standardized applications, and until such data are available, clinicians and consumers should exercise caution to ensure safe and effective dermatological practices, particularly with intravenous use

Arslan, S.A., I

Sterile syringe

But increasing the amount of glutathione in this manner is difficult for a few different reasons: In short, the average nutritional supplement (or food source) is ill-suited for the task of restoring glutathione