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Polymers, which can be natural or synthetic [e.g., chitosan, poly (lactic acid) (PLA), poly (glycolic acid) (PGA)], exhibit excellent biocompatibility and biodegradability, making them suitable for various delivery routes (Harun-Or-Rashid et al., 2023)
Thus, while the effects of general anesthesia on cortical gene expression are consistent with the strong repression of brain activity, further deleterious effects are apparent including a reactive astrocyte profile
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