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The bioactive metabolite berberrubine has shown additional efficacy in NAFLD models [81]

Carnitine is a nutrient that naturally occurs in the body and is essential to the process of proper fat metabolism in muscle and other tissue

They are biodegradable, biocompatible, and chemically stable, have low toxicity, and improve targeting, bioavailability, and sustainability of drugs 27

[166] demonstrated that pretreatment of 7 day old rat pups with the acetylcholinesterase inhibitor galantamine (5mg/kg injected i.p.) 2 hours prior to HI led to significantly reduced damage in the hippocampus and cortex at 7 days after injury [166]